Most populous state capital
Most populous U.S. city that isn't a county seat
Most poverty-stricken
Most powerful club?
Most powerful men on board, but not at court
Most powerful piece in Stratego
Most powerful primate
Most powerful workstation
most powerful, rich, or gifted members of a group
Most precious
Most precipitous
Most preferred
Most prestigious
Most prestigious exemplar
Most Prestwick Airport patrons
Most pretentious
most prevalent gas in air
Most prevalent grape in Chianti
Most pricey
Most pricy
Most priests
Most prized
Most prized, often
most probably
Most proficient
Most profound
Most profs
Most prolific Hollywood actor, per IMDb
Most prom attendees
Most promgoers (Abbr.)
most prominent
Most prominent person in a field
most prominent point at the back of the head
Most prominent position
Most promising
Most promising slate of candidates
Most promptly
Most prone to be impudent
Most prone to brooding
Most prone to play "Grand Theft Auto V" and eat Doritos all day
Most prone to preening
Most prone to prying
Most prone to sunburn
Most protected
Most provocative
Most proximate
Most prudent
Most prudent, as advice
Most prying
Most pucker-inducing
most puzzles heading
Most qualified
Most qualified to serve
Most quick-to-learn
Most quickly
Most quirky
Most racers, after the race
most rapid
Most rappers don't use them
Most rare
Most rational
Most ready
Most ready for picking
Most ready for plucking
Most ready for trouble
Most ready to be picked
Most real
most real and correct
Most reasonable
most recent
Most recent 007
Most recent 600-homer club member
Most recent box office arrival, probably
most recent info
most recent info with the
Most recent news
most recent or newest
most recent or ultimate
Most recently
Most recently born
Most recently introduced
Most recently made
Most recently produced
Most recently released
Most reckless
Most recycled metal on Earth
Most red
Most red in the middle
Most red, maybe
Most reliable
Most religiously homogeneous state in America
Most remarkable person
Most Rembrandts
most remote
Most remote from reputable
Most remote, briefly
Most repellent
Most reprehensible
Most repulsive
Most reserved
Most resourceful
Most respected expert
most respected person in a field
Most respectful (of)
Most restricted, filmwise
Most ret. people
Most retirees: Abbr.
Most revealing
Most revolting
Most ridiculous, as an excuse
Most rigid
most riotous
Most Ripleyesque
Most robust
Most rough-sounding
Most rough, in a manner of speaking?
Most rundown
most rushed
Most sacred
Most sacred building in Islam
Most sagacious
Most sarcastic
Most sarcastic, as remarks
Most sardonic
Most SAT takers
Most saucy
Most Saudis
Most Saudis and Iraqis
Most scant
Most scantily dressed
Most scanty
Most scarce
Most scorching
Most scoutmasters
Most scurrilous
Most secure
Most see-through
Most seldom seen
most self satisfied
most self satistfied
Most self-satisfied
Most senators
Most senior
Most senior member of a group
Most senior of two
Most senseless
Most sensible
Most sensitive
Most serene
Most serious
Most serious kind of flu
Most serious, as a felony
Most severe
Most shaggy / Hotel offering / Actress Goldie
Most shameful
Most sharp
Most sharply inclined
Most sheltered
Most shipshape
Most shoddy
most sick
Most sickly
Most significant
Most significant entitlement
Most significantly, in texting
Most silly
Most silverware, actually
Most similar to the Sahara
Most simple
most simple not hard at all
Most sincere
Most sinuous
Most skilled
Most skillful
Most skittish
Most sky-colored
Most slapstick
most sleazy
Most sleepy
Most slim
Most slippery
Most slow-witted
Most slush pile responses
Most small-minded
Most smart
Most smooth and lustrous
Most smooth and stylish
Most smooth, as peanut butter
Most snarky
Most sneaky
most snobbish
Most snug
most soaked
Most Soc. Sec. beneficiaries
Most Soc. Sec. recipients
Most socially conscious
Most soiled
Most soldiers
most solid
Most sophisticated
Most sordid
Most sore
MOST SORROWFUL
Most sought-after party guests
Most sound
Most sound, mentally
Most sour
Most sour-tasting
Most spacious
Most spam
Most spare
Most sparse
Most sparsely furnished
Most sparsely populated Eur. country
Most sparsely populated European country
Most Spartan
Most spick-and-span
Most spicy
Most spiders have eight
Most spiffy
Most spine-tingling
most spiteful
Most sporting
Most sports fans
Most spotless
most sprightly
Most spruce
Most stable
Most stale
Most stale and moldy
Most standoffish
Most starfish have five
Most state-of-the-art
Most steaks
most stern
Most sticky, as a sweet treat
Most stiffly proper
Most stomach-turning
Most straight, as wheels
Most strange
Most strapping
Most stretched
Most strict
Most strongly built
Most stuck-up
Most student drivers
Most Stuf cookie
Most stylish
Most subdued
most submissive