The "home" in John Denver's "Take Me Home, Country Roads"
The "Homo" in "Homo sapiens"
The "Homo" of "Homo sapiens"
The "I" in "The King and I"
The "I" in 23-Down
The "I" in E. I. du Pont
The "I" in F.W.I.W.
The "I" in I. M. Pei
The "I" in I.B.M.: Abbr.
The "I" in ICBM
The "I" in IHOP: Abbr.
The "I" in IUD
The "I" in IV
The "I" in M.I.T.: Abbr.
The "I" in MIT (abbr.)
The "I" in ROYGBIV
The "I" in T.G.I.F.
The "I" in TGIF
The "I" in the answer to 1-Across
The "I" in VMI: Abbr.
The "I" of "How I Met Your Mother"
The "I" of "The King and I"
The "I" of Canada's P.E.I.
The "I" of Claudius I
The "I" of E. I. du Pont
The "I" of Elizabeth I?
The "I" of F.Y.I., for short
The "I" of FBI, e.g.
The "I" of FWIW
The "I" of I. M. Pei
The "I" of I.M.F.: Abbr.
The "I" of I.P.A.
The "I" of ICBM
The "I" of IM
The "I" of IM, sportswise
The "I" of IV
The "I" of literature's "Reader, I married him"
The "I" of R.P.I.: Abbr.
The "I" of T.G.I.F.
The "id" in "id est"
The "Iliad" and the "Odyssey"?
The "Iliad" or "Odyssey"
The "Iliad" or The "Odyssey"
The "in" thing
The "Incredible Hulk" creator
The "industry" state
The "ipso" in ipso facto
The "Ishtar" of cars
The "It Girl" Bow
The "it" game?
The "it" in "He likes it! Hey Mikey!"
The "it" in "I don't want to talk about it"
The "it" in "Step on it!"
The "it" in 20-Across, maybe
The "it" in the 1990s slogan "Gotta have it"
The "it" in the lyric "turn it on, wind it up, blow it out"
The "it" of "Because it's there"
The "izn" in shiznit, e.g., to a linguist
The "J. D." of J. D. Salinger
The "J." in Mary J. Blige
The "J" of J. K. Rowling
The "J"s in J. J. Abrams, e.g.
The "joe" of a cup of joe
The "Judy" of Punch and Judy
The "Julius" of Gaius Julius Caesar, e.g.
The "K" in James K. Polk
The "k" in kg
The "K" of "KCMO"
The "K" of James K. Polk
The "k" of kHz
The "K" of RKO
The "kid" of "Here's looking at you, kid"
The "king of kings," per a famous sonnet
The "king" in "The Last King of Scotland"
The "Kitchen of Japan"
The "L" in "SNL"
The "L" in 5-Across
The "L" in 51-Down
The "L" in 57-Across
The "L" in AWOL
The "l" in craigslist's slo page
The "L" in L.A.
The "L" in LASIK
The "L" in N.L. or A.L.
The "L" in NHL
The "L" in S.&L.
The "L" in the Broadway monogram "L.M.M."
The "L" in this store's logo hints at the store's name
The "L" in UCLA
The "L" in URL
The "L" in XL: Abbr.
The "L" in XXL
The "L" of "A = L x W"
The "L" of A.F.L.-C.I.O.
The "L" of AWOL
The "L" of B.L.M.
The "L" of L. Frank Baum
The "L" of L.A.
The "L" of L.A.P.D.
The "L" of L.C.D.
The "L" of L.G.B.T.Q.
The "L" of LSAT
The "L" of MLK
The "L" of N.F.L.
The "L" of S.L.R.
The "L" of U.C.L.A.
The "L" of U.N.L.V.
The "L" of XL
The "L" of XXL
The "Li'l" guy
The "little blue pill"
The "logs" in "ants on a log"
The "love" in "my only love sprung from my only hate!"
The "m" in E = mc^2
The "M" in E=MC2
The "m" in Einstein's formula
The "m" in m-1 rifle
The "m" in me
The "M" in MSG
The "M" in MVP
The "m" in the equation "F = ma"
The "m" in the equation y = mx + b
The "M" in USMC
The "M" in Y.M.C.A.
The "m" of "yes'm"
The "m" of E = mc squared
The "m" of E = mc^2
The "m" of F = ma
The "M" of IMDb
The "M" of M.D.: Abbr.
The "m" of m.e.
The "M" of MB
The "M" of MCAT (abbr.)
The "M" of MHz
The "M" of MTV
The "M" of NASA's LEM
The "M" of STEM, for short
The "M" of Y.M.C.A.
The "Macarena" dance was one
The "Macbeth" witches, e.g.
The "madam" in "Madam, I'm Adam"
The "Mahabharata" or the "Ramayana"
The "me" in "Roger & Me"
The "me" of "Despicable Me"
The "merry" part of a "merry game"
The "missing link," for one
The "Mistress of the Dark"
The "mode" in ala mode
The "Moonlight," e.g.
The "mother" of deposits
The "Motown sound," e.g.
The "murder hornet" is one
The "N" in "INCO"
The "N" in "N x P"
The "N" in NAJA
The "N" in NAS
The "N" in NASA: Abbr.
The "N" in NCO
The "N" in NDA
The "N" of CSNY
The "N" of N.A.A.C.P.: Abbr.
The "N" of N.B.
The "N" of N.B.A.: Abbr.
The "N" of N.F.L.: Abbr.
The "N" of NGO
The "N" of PIN
The "N" of RN
The "N" of TNT
The "N" of TV's NPH
The "N" of U.N.C.F.
The "N" of U.S.N.A.
The "Na" in NaCl
The "Nautilus"' captain
The "needle" part of needle grass
The "Nine-Nine" of TV's "Brooklyn Nine-Nine"
The "non-existent" contraction
The "nonexistent" contraction
The "O's" of Cheerios
The "O" in B.O.
The "O" in BYOB
The "O" in CD-ROM
The "O" in F. A. O. Schwarz
The "O" in football's OBJ
The "O" in G.O.P.
The "O" in IOU
The "O" in Jackie O.
The "O" in M.Y.O.B.
The "O" in NATO (abbr.)
The "O" in OAS: Abbr.
The "O" in Ogden Nash's alphabet of baseball players
The "O" in P.L.O.: Abbr.
The "O" in R.E.O.
The "o" in Reo
The "O" in REO cars
The "O" in ROM
The "O" in S.R.O.
The "O" in television's OWN
The "O" in the Dallas Cowboys' T.O.
The "O" in XO
The "O" of A.O.C.
The "O" of B.&O.
The "O" of B.Y.O.B.
The "O" of B&O Railroad
The "O" of CD-ROM
The "O" of Cheerios
The "O" of Jackie O.
The "O" of O Magazine
The "O" of OWN
The "O" of S O S, apocryphally
The "O" of S O S, supposedly
The "O" of the magazine O
The "O" of the OWN Network
The "o" of Verizon's Fios
The "o" of xo
The "Odyssey" is its sequel
The "Odyssey" is one
The "Odyssey" or "Beowulf"
The "one" in "the old one-two," maybe
The "one" in a one-two
The "one" in a one-two punch
The "one" in the phrase "draw one"
The "one" of a one-two
The "ones" in one-twos
The "op." of "op. cit"
The "oven" in "have a bun in the oven"
The "P" in "PCS"
The "P" in "ASAP"
The "P" in "CPR"
The "P" in a Latin R.I.P.
The "P" in E.A.P.
The "P" in IPA
The "p" in m.p.g.
The "p" in m.p.h.
The "p" in mpg
The "P" in P.G. Wodehouse
The "P" in P.T.A.
The "P" in PIN: Abbr.
The "P" in PMS
The "P" in POTUS: Abbr.
The "p" in r.p.m.
The "p" in rpm
The "P" in TAFKAP
The "p" in the middle of certain abbreviations
The "P" in UPS
The "p" in wpm
The "P" of 23-Down
The "p" of 6p
The "p" of b.p.s.
The "P" of G.O.P.
The "p" of m.p.h.